# KNOW TAU Mechanism of Disease
Keywords: tau pathology, Alzheimer's disease, amyloid-beta, tau tangles, Braak staging, tau aggregation, neurodegeneration

> This page provides an educational overview of tau pathology in Alzheimer's disease, including its relationship with amyloid-beta, the progression of tau tangles, and their impact on neuronal function and clinical symptoms. It also offers additional learning resources for healthcare professionals.

## Details
- [Tau Pathology Overview](#): This video explains the evolving understanding of tau pathology in Alzheimer's disease, focusing on its progression and impact on neuronal function and clinical symptoms.
- [Educational Module](#): Learn more about concepts such as Braak staging, tau aggregation, and the role of tau in neurodegeneration in Module 1.
- [Program Disclaimer](#): This program is for informational purposes only, does not provide CME credit, and is intended for healthcare professionals. Developed and funded by Biogen.
- [Biogen Reference](#): Biogen-265550 | February 2026.